| Factors |
Fibrinogen |
Control |
p-valuec) |
| No of patients |
168 |
1.708 |
|
| Preoperative factors |
| Preoperative platelets inhibitors |
28 (16.7%) |
159 (9.3%) |
0.0037 |
| Neurologic dysfunction |
21 (12.5%) |
143 8.4%) |
0.0908 |
| S-creatinine >200 µmol/ L |
8 (4.8%) |
54 (3.2%) |
0.3783 |
| Female |
38 (22.6%) |
515 (30.2%) |
0.0506 |
| Age (mean) |
64.4 ± 14.4 |
64.6 ± 13.5 |
0.8187 |
| Euroscore (mean) |
8.0 ± 4.3 |
5.9 ± 3.7 |
<0.0001 |
| EuroSCORECardiac state (mean) |
1.2 ± 1.8 |
1.2 ± 1.6 |
0.5517 |
| Pre op. patient factors comp (Euroscore)a) |
1.5 ± 2.1 |
0.8 ± 1.4 |
<0.0001 |
| EuroSCORE age/sex (mean) |
2.3 ± 1.9 |
2.4 ± 2.0 |
0.7298 |
| EuroSCORE procedure (mean) |
2.6 ± 2.0 |
1.4± 1.5 |
<0.0001 |
| Coronary artery bypass graftingb) |
60 (35.7%) |
999 (58.5%) |
<0.0001 |
| Aortic valve replacementb) |
62 (36.9%) |
555 (32.5%) |
0.2824 |
| Mitral valve replacementb) |
24 (14.3%) |
167 (9.8%) |
0.0873 |
| Total valve replacementb) |
83 (49.4%) |
712 (41.7%) |
0.0643 |
| Aortic surgery |
35 (20.8%) |
60 (3.5%) |
<0.0001 |
| Other than CABG, valve- or aortic surgery |
23 (13.7%) |
243 (14.2%) |
0.7165 |
| Perioperative re-combinant fact VII |
20 (11.9%) |
3 (0.2%) |
<0.0001 |
| Peroperative Aprotinin |
19 (11.3%) |
109 (6.4%) |
0.0240 |
| Postoperative outcomes |
| Neurologic dysfunction (stroke) |
11 (6.5%) |
32 (1.9%) |
0.0003 |
| Myocardial infarction |
9 (5.4%) |
48 (2.8%) |
0.1082 |
| Need for dialysis |
23 (13.7%) |
63 (3.7%) |
<0.0001 |
| 30-day mortality |
9 (5.4%) |
42 (2.5%) |
0.0505 |
