Patients characteristics |
Median |
Range |
Sex ratio (M/F) |
0.95 |
- |
Age at diagnosis of ITP (years) |
9.6 |
(0.8-16.5) |
Hemorrhage score (Buchanan) at diagnosis |
2 |
(0-4) |
Platelet count at diagnosis (G/L) |
10 |
(1-99) |
Time from diagnosis to splenectomy (months) |
24.0 |
(1-162) |
Age at splenectomy (years)1 |
12.4 |
(3.5-17.4) |
Number of previous specific treatments2 |
2 |
(1-7) |
Hemorrhage score (Buchanan) at splenectomy |
1 |
(0–5) |
Minimal platelet count before splenectomy (G/L) |
4 |
(1-27) |
^{1}3 children (4%) were between 3 and 5 years old at the time of splenectomy
^{2}All the children had received at least one specific platelet-enhancing treatment
before splenectomy: first-line treatment: IVIg (median 8 courses, 1 to 96) (n=75)
and / or steroids (n=74), second-line treatment (n=29): rituximab (n=11), anti-D
(n=10), hydroxychloroquine (n=6), vinblastine (n=5), cyclosporine (n=5), azathioprine
(n=3), mycophenolate mofetil (n=3), dapsone (n=2), eradication of H. Pylori
(n=2), colchicine (n=1), interferon alpha (n=2). |