| |
Period , number of institutions, number of patients |
Median age at diagnosis of ITP (y) |
Median age at splenectomy (y)1 |
Median delay diagnosis - splenectomy (y)2 |
Median follow up (y) |
Global response at last follow- up4 |
Peri- operative bleeding(n) |
OPSI |
| El Hafy et al, 2004 Egypte |
1980 – 1996 1 institution
N = 112 |
NA3 |
9.5 (6 – 16) |
0.8 (0.3 – 2.6) |
9 (5 – 16) |
45%
> 100 G/L |
NA |
0 death 2 pneumococcal sepsis hospitalized (1 immunization, 2 prophylaxis) |
| Aronis et al,2004Greece |
1975 – 2002
1 institutionN = 33 |
NA |
12 |
3.3 (0.6 – 14.5) |
18.8 (6 – 25) |
85%
> 150 G/L |
2 |
1 death, septic shock(no immunization, no prophylaxis)No sepsis |
| Donato et al,2006Italy |
1981-2005
1 country, 7 institutionsN = 30 |
8 |
NA |
2.5 (1 – 6) |
4.9 (1 – 13) |
73%
> 150 G/L |
NA |
0 death
Sepsis not specified |
| Ramenghi etal, 2006Argentina |
NA - 2002
1 country, 11 institutionsN = 90 |
8 (1.3 – 17.8) |
11.3 (2.4 – 22.4) |
2.4 ( 0.5 – 19.4) |
3.9 (0.4 – 15) |
75%
> 50 G/L |
NA |
1 death, sepsis(immunization and prophylaxis
NA) 10 “infectious episodes” |
| Kühne et al,2007ICIS |
1997 – 2006
25 countries, 57institutions N = 134 |
9.5 (1.1 – 18.7) |
11.8 (2.7 – 20.7) |
1.8 (0.1 – 10.8) |
2 (0.1 – 4.5) |
69%
> 150 G/L |
8 |
0 death
7 sepsis |
| Our study,2011France |
2000 – 2009
1 country, 16 institutions
N = 78 |
9.6 (0.8 – 16.5) |
12.4 (3.5 – 17.4) |
2 (0.1 – 13.5) |
3.4 (0.1 – 13.5) |
84%
> 100 G/L
51% in CCR |
2 |
0 death
No sepsis |
