|Sepsis Beyond The Initial 6 HOURS
RBC transfusion is indicated for patients with evidence of hemorrhagic shock.
A “restrictive” strategy of RBC transfusion (transfuse when Hb < 7 g/dL) in patients with hemodynamically stable anemia,
In the absence of acute hemorrhage RBC, transfusion should be given as single units.
Consider transfusion if Hb < 7 g/dL in patients with stable cardiac disease. There is no benefit of a “liberal” transfusion strategy (when Hb < 10 g/dL) in patients with stable cardiac disease.
RBC transfusion may be beneficial in patients with acute myocardial ischemia who are anemic (Hb < 8g/dL).
Within 6 Hours of Severe Sepsis
Transfuse RBC when Hb < 10 g/dL to achieve ScvO2 =70% (only after CVP of 8 -12 mmHg and MAP > 65mmHg are achieved)