Sepsis Beyond The Initial 6 HOURS
       RBC transfusion is indicated for patients with evidence of hemorrhagic shock.
       A “restrictive” strategy of RBC transfusion (transfuse when Hb < 7 g/dL) in patients with hemodynamically stable anemia,
      In the absence of acute hemorrhage RBC, transfusion should be given as single units.
      Consider transfusion if Hb < 7 g/dL in patients with stable cardiac disease. There is no benefit of a “liberal” transfusion strategy (when Hb < 10 g/dL) in patients with stable cardiac disease.   
     RBC transfusion may be beneficial in patients with acute myocardial ischemia who are anemic (Hb < 8g/dL).
Within 6 Hours of Severe Sepsis
       Transfuse RBC when Hb < 10 g/dL to achieve ScvO2 =70% (only after CVP of 8 -12 mmHg  and MAP > 65mmHg are achieved)
Table 3: Guidelines for RBC Transfusion in Sepsis.