Stress condition

Peak Purity 

Single point  threshold

% degraded (both Metformin and sulfonylurea)

GPZ

GBD

GMD

GPZ

GBD

GMD

GPZ

GBD

GMD

Light

1.0000

1.0000

1.0000

0.9999

0.9999

0.9999

Nil

Nil

Nil

Heat

1.0000

1.0000

1.0000

0.9999

0.9999

0.9999

Nil

Nil

Nil

Acid

1.0000

1.0000

1.0000

0.9999

0.9999

0.9999

 0.71

1.94

0.05

Base

1.0000

1.0000

1.0000

0.9999

0.9999

0.9999

0.51

0.50

1.67

Oxidation

1.0000

1.0000

1.0000

0.9999

0.9999

0.9999

25.86

38.0

27.0

Table 1: Results of Forced degradation study of GPZ, GBD and GMD.