Positiona |
Zolmitriptan |
Isomeric Peak-1 |
Isomeric Peak-2 |
Isomeric Peak-3 |
Isomeric Peak-4 |
1H, (ppm)(Hz) |
13C |
DEPT |
1H, (ppm)(Hz) |
13C |
DEPT |
1H, (ppm)(Hz) |
13C |
DEPT |
1H, (ppm)(Hz) |
13C |
DEPT |
1H, (ppm)(Hz) |
13C |
DEPT |
1 |
1H, 10.68 (brs) |
- |
- |
1H, 10.87 (s) |
- |
- |
1H, 11.06(s) |
- |
- |
1H, 10.58(s) |
- |
- |
1H, 10.72(s) |
- |
- |
2 |
1H, 7.10 (dj=2.08) |
122.97 |
CH |
1H, 7.00-7.06(m) |
122.64 |
CH |
- |
134.28 |
Q |
1H, 7.10(d) |
122.76 |
CH |
1H, 7.15(d) |
123.19 |
CH |
3 |
- |
112.72 |
Q |
- |
112.95 |
Q |
- |
109.45 |
Q |
- |
112.92 |
Q |
- |
112.42 |
Q |
4 |
1H, 7.34(s) |
119.13 |
CH |
- |
123.7 |
Q |
1H, 7.38-7.40(m) |
118.9 |
CH |
1H, 7.36-7.40(m) |
118.19 |
CH |
1H, 7.44(s) |
119.48 |
CH |
5 |
- |
126.17 |
Q |
- |
135.26 |
Q |
- |
128.96 |
Q |
- |
128.5 |
Q |
- |
135.08 |
Q |
6 |
1H, 6.91-6.93(dd) |
122.86 |
CH |
1H, 7.00-7.06(m) |
123.96 |
CH |
1H, 6.97(d) |
123.15 |
CH |
1H, 7.00(s) |
123.54 |
CH |
- |
123.83 |
Q |
7 |
1H, 7.24 (d,j=8.24) |
111.61 |
CH |
1H,7.20-7.34(m) |
110.82 |
CH |
1H, 7.27(d) |
111.02 |
CH |
- |
124.59 |
Q |
1H, 7.09(s) |
112.48 |
CH |
8 |
- |
135.39 |
Q |
- |
135.62 |
Q |
- |
134.96 |
Q |
- |
135.42 |
Q |
- |
135.08 |
Q |
9 |
- |
127.79 |
Q |
- |
125.56 |
Q |
- |
126.35 |
Q |
- |
126.61 |
Q |
- |
126.76 |
Q |
10 |
4H, 2.75-2.91(m) |
40.75 |
CH2 |
2H, 2.52-2.93(m) |
40.35 |
CH2 |
2H, 2.79-2.97(m) |
40.54 |
CH2 |
2H, 2.80-2.95(m) |
40.41 |
CH2 |
2H, 2.70-3.01(m) |
40.12 |
CH2 |
11 |
3H, 4.00-4.249m) |
53.37 |
CH |
1H, 3.79-4.39(m) |
53.39 |
CH |
1H, 4.02-4.33(m) |
53.09 |
CH |
1H, 4.04-4.34(m) |
53 |
CH |
1H, 3.69-4.34(m) |
52.47 |
CH |
12 |
3H, 4.00-4.24(m) |
68.5 |
CH2 |
2H, 3.79-4.39(m) |
68.37 |
CH2 |
2H, 4.02-4.33(m) |
67.97 |
CH2 |
2H, 4.04-4.34(m) |
68.04 |
CH2 |
2H, 3.69-4.34(m) |
68.18 |
CH2 |
14 |
- |
159-26 |
-C=O |
- |
158.47 |
-C=O |
- |
158.59 |
-C=O |
- |
158.58 |
-C=O |
- |
158.45 |
-C=O |
16 |
1H, 7.75(s) |
- |
- |
1H, 7.52(s) |
- |
- |
-1H, 7.76(s) |
- |
- |
1H, 7.80(s) |
- |
- |
1H, 7.80(s) |
- |
- |
17 |
2H, 2.48-2.52(m) |
- |
- |
2H, 1.80-2.07(m) |
23.96 |
CH2 |
2H, 2.79-2.97(m) |
22.7 |
CH2 |
2H, 2.80-2.95(m) |
22.98 |
CH2 |
2H, 2.70-3.01(m) |
23.01 |
CH2 |
18 |
4H, 2.75-2.91(m) |
- |
- |
2H, 1.80-2.07(m) |
61.38 |
CH2 |
2H, 2.50-2.53(m) |
59.89 |
CH2 |
2H, 2.53(t) |
59.85 |
CH2 |
2H, 2.54(t) |
59.99 |
CH2 |
20 |
6H, 2.21(s0 |
- |
- |
3H, 1.80-2.07(m) |
44.65 |
CH3 |
3H, 2.23(s) |
45.12 |
CH3 |
3H, 2.23(s) |
45.12 |
CH3 |
3H, 2.24(s) |
45.12 |
CH3 |
21 |
6H, 2.21(s) |
- |
- |
3H, 1.80-2.07(m) |
44.65 |
CH3 |
3H, 2.23(s) |
45.12 |
CH3 |
3H, 2.23(s) |
45.12 |
CH3 |
3H, 2.24(s) |
45.12 |
CH3 |
22 |
- |
- |
- |
- |
138.06 |
Q |
1H, 7.38-7.40(m) |
129.75 |
CH |
1H, 7.36-7.40(m) |
129.83 |
CH |
1H, 7.31(d) |
129.15 |
Q |
23 |
- |
- |
- |
1H, 7.20-7.34(m) |
129-84 |
CH |
1H, 7.56(d) |
127.48 |
CH |
1H, 7.59(d) |
128.21 |
CH |
1H, 7.25(d) |
129.4 |
CH |
24 |
- |
- |
- |
1H, 7.20-7.34(m) |
128.27 |
CH |
- |
135.65 |
Q |
- |
137.05 |
Q |
- |
140.69 |
CH |
25 |
- |
- |
- |
1H, 7.20-7.34(m) |
128.87 |
CH |
1H, 7.56(d) |
127.48 |
CH |
1H, 7.59(d) |
128.21 |
CH |
1H, 7.25(d) |
129.4 |
Q |
26 |
- |
- |
- |
1H, 7.20-7.34(m) |
130.32 |
CH |
1H, 7.38-7.40(m) |
129.75 |
CH |
1H, 7.36-7.40(m) |
129.83 |
CH |
1H, 7.31(d) |
129.15 |
CH |
27 |
- |
- |
- |
- |
133.48 |
Q |
- |
131.24 |
Q |
- |
132.25 |
Q |
- |
134.61 |
CH |
28 |
- |
- |
- |
2H, 2.52-2.93(m) |
37.53 |
CH2 |
2H, 2.79-2.97(m) |
39.92 |
CH2 |
2H, 2.80-2.95(m) |
39.92 |
CH2 |
2H, 2.70-3.01(m) |
38.3 |
CH2 |
29 |
- |
- |
- |
1H, 3.79-4.39(m) |
52.85 |
CH |
1H, 4.02-4.33(m) |
52.36 |
CH |
1H, 4.04-4.34(m) |
52.53 |
CH |
1H, 3.69-4.34(m) |
52.36 |
CH |
30 |
- |
- |
- |
2H, 3.79-4.39(m) |
68.49 |
CH2 |
2H, 4.02-4.33(m) |
68.03 |
CH2 |
2H, 4.04-4.34(m) |
68.04 |
CH2 |
2H, 3.69-4.34(m) |
68.18 |
CH2 |
32 |
- |
- |
- |
- |
158.79 |
-C=O |
- |
-158.64 |
-C=O |
- |
158.69 |
-C=O |
- |
158.74 |
-C=O |
34 |
- |
- |
- |
1H, 7.67(s) |
- |
- |
-1H, 7.83(s) |
- |
- |
1H, 7.82(s) |
- |
- |
1H, 7.54(s) |
- |
- |
s: singlet; d: doublet; brs: broad singlet; J: coupling constant; Q: quaternary carbon.
aRefer structures for numbering (Figure 1) |