| |
Sham |
ICS1 |
ICS2 |
ICS4 |
LABA1 |
LABA2 |
LABA4 |
| TT (N/cm2) |
4.2 ± 0.4 |
4.3 ± 0.5 |
4.0 ± 0.3 |
4.0 ± 0.6 |
4.4 ± 0.3* |
4.3 ± 0.3* |
4.6 ± 0.4* |
| CT (msec) |
39.4 ± 1.9 |
34.3 ± 1.7* |
32.4 ± 1.5** |
42.1 ± 2.0 |
34.8 ± 3.3 |
41.1 ± 1.8 |
36.1 ± 1.8 |
| HRT (msec) |
45.0 ± 4.6 |
34.2 ± 2.7*** |
36.9 ± 2.9** |
54.0 ± 5.3 |
44.9 ± 6.8 |
50.5 ± 6.2 |
40.1 ± 2.9 |
| Fatigue (%) |
39.9 ± 3.6 |
33.4 ± 2.7 |
32.5 ± 2.2 |
36.8 ± 2.4 |
33.4 ± 1.9 |
37.9 ± 2.4 |
36.6 ± 2.4 |
| TT/CT (N/cm2/sec) |
95.3 ± 13.3 |
127.4 ± 13.9 |
125.2 ± 8.0 |
93.5 ± 10.9† |
129.0 ± 9.9 |
106.8 ± 9.0 |
131.0 ± 15.6 |
| (TT/2)/HRT (N/cm2/sec) |
43.0 ± 7.2 |
64.9 ± 7.8 |
55.6 ± 3.0 |
39.0 ± 5.6†† |
55.8 ± 7.6 |
45.9 ± 4.6 |
58.9 ± 5.6 |
ICS1, ICS2, and ICS4 express 1 h, 2 h, and 4 h after ICS inhalation. LABA1, LABA2, and LABA4 express 1 h, 2 h, and 4 h after LABA inhalation.
TT: Twitch Tension; CT: Contraction Time; HRT: Half-Relaxation Time.
*p<0.05, **p<0.01, ***p<0.001. compared with sham.
†p<0.05, ††p<0.01 compared with each value at ICS1. |
