TRAPEZIUS Time (min) 20 40 60 80 100 120 140 160 180 200 220 Dtot CM CM/Dtot OEA   A 35.4                     35.4 130.8 3.7 B 7.9 28.8 DM 50.8 32.1             119.6 106.9 0.9 C 40.1 363.2 59.5 25.8 29.9 90 29.1         637.5 146 0.2 D 65.3 107.7 162.3 66.5 95.2 70.8 109.3 46.4 57.6 16.6 24.4 822 277 0.3   PEA                             A 14.8                     14.8 149 10.1 B 10 23 DM 39.8 27.8             100.7 162.1 1.6 C 36.6 104.7 35.2 22.4 60.5 23.1 24.6         307 161.3 0.5 D 59.1 40 105.2 57.4 46.3 34.1 49 24.9 29 9.5 15.3 469.8 222.6 0.5   SEA                             A 2.8                     2.8 85.6 31.1 B 4.1 6.6 DM 16.7 6             33.4 117.8 3.5 C 17.3 21.6 24.8 7.3 20.8 5.9 14.1         111.8 110.3 1 D 24.9 26.2 58 38 27 31.2 19 4.6 15 3.4 2.5 249.6 107.8 0.4   2AG                             A _                       3066.9   B _ _ _ DET _               1374.5   C _ _ _ _ _ DET _           483.7   D _ _ DET _ _ _ _ _ _ _ _   1961.8     AEA                             A _                       _   B _ _ _ _ _               DET   C _ 47.6 _ _ _ _ _           DET   D _ _ _ 36.2 _ _ _ _ _ _ _   DET   SKIN OEA   A 256.3                     256.3 220.5 0.9 B DM 126 120.1 DM DM             246 236.7 1 C 164 138.6 185.5 267.6 49.3 78.3 7.5         890.8 304.7 0.3                               PEA   A 74.7                     74.7 133.9 1.8 B DM 29.4 24 DM DM             53.4 96 1.8 C 62.5 50.5 49.7 81.8 9.8 23.5 8.5         286.2 137.2 0.5                               SEA   A 176.9                     176.9 315.2 1.8 B DM 70.5 107.4 DM DM             177.9 317 1.8 C 126.3 153.2 208.1 307.5 96.2 85.5 31.1         1007.8 402.4 0.4                               2AG   A _                       845.1   B _ _ _ _ _               70.8   C _ _ _ _ _ _ _           134.1

Table 1: OEA, PEA and SEA levels in fmol from each time point from human trapezius muscle and forearm skin. A, B, C and D represent the different catheters. Dtot is the sum of moles in dialysate collected from each catheter. CM is the catheter membrane levels. CM/Dtot is a quota and presents the dimension of the relative adsorption. DM equals dialysate missing, or dialysate volume too small for measurement, and could be due to problems with the MD pump or to a failure in the membrane throughput. DET denotes detected but not quantifiable levels.