| Mixture |
%RC |
| FOS |
DEX |
OND |
| t7 |
t15 |
t7 |
t15 |
t7 |
t15 |
| 1 |
99.00 ± 3.00 |
99.00 ± 0.70 |
102.50 ± 0.50 |
100.00 ± 0.06 |
95.10 ± 0.30 |
96.00 ± 0.90 |
| 2 |
100.10 ± 0.30 |
97.80 ± 1.70 |
102.50 ± 1.50 |
100.50 ± 0.13 |
98.00 ± 1.30 |
97.00 ± 0.90 |
| 3 |
98.30 ± 0.60 |
96.40 ± 0.90 |
96.06 ± 1.22 |
98.00 ± 0.50 |
92.50 ± 0.23 |
95.20 ± 0.90 |
| 4 |
93.10 ± 0.50 |
92.30 ± 0.90 |
94.00 ± 5.00 |
98.30 ± 2.50 |
96.70 ± 0.30 |
99.60 ± 1.90 |
| 5 |
100.20 ± 0.60 |
97.60 ± 1.70 |
97.30 ± 2.50 |
99.70 ± 0.14 |
99.20 ± 1.02 |
99.10 ± 0.21 |
| 6 |
97.00 ± 5.00 |
97.50 ± 1.40 |
100.70 ± 0.30 |
99.90 ± 0.30 |
99.30 ± 0.50 |
99.40 ± 1.00 |
| 7 |
97.00 ± 6.00 |
95.00 ± 6.00 |
98.00 ± 0.03 |
96.30 ± 0.40 |
98.70 ± 0.90 |
98.10 ± 0.40 |
| 8 |
99.40 ± 0.15 |
99.30 ± 0.50 |
98.60 ± 0.90 |
97.80 ± 0.50 |
98.00 ± 3.00 |
95.70 ± 0.20 |
| 9 |
98.00 ± 3.00 |
99.10 ± 1.09 |
99.10 ± 0.80 |
98.70 ± 0.90 |
99.10 ± 1.50 |
96.90 ± 1.30 |
| 10 |
100.70 ± 1.00 |
90.00 ± 3.00 |
97.50 ± 0.10 |
97.70 ± 0.30 |
99.70 ± 0.50 |
99.60 ± 0.60 |
| 11 |
96.50 ± 0.90 |
96.60 ± 0.80 |
98.10 ± 1.12 |
96.80 ± 0.80 |
94.80 ± 0.40 |
93.60 ± 0.30 |
| 12 |
96.40 ± 1.15 |
96.30 ± 0.30 |
93.00 ± 1.19 |
94.30 ± 1.17 |
92.00 ± 5.00 |
91.90 ± 0.90 |
|
FOS: Fosaprepitant DEX: Dexamethasone OND: Ondansetron
%RC: Percentage of remaining drug concentration ± standard deviation
t7: 7 days of storage
t15: 15 days of storage |
| Table 5: Percentage of remaining concentrations of FDO in mixtures at day 7 and 15 of storage. |
