Mixture |
%RC |
FOS |
DEX |
GRA |
t7 |
t15 |
t7 |
t15 |
t7 |
t15 |
13 |
98.9 ± 1.30 |
99.7 ± 0.40 |
99.7 ± 0.30 |
97.8 ± 2.40 |
99.8 ± 0.16 |
98.9 ± 0.90 |
14 |
98.4 ± 0.50 |
98.8 ± 1.00 |
100.3 ± 0.80 |
99.8 ± 0.13 |
98.7 ± 0.30 |
98.8 ± 0.70 |
15 |
99.4 ± 0.70 |
93.5 ± 0.50 |
99.5 ± 1.21 |
98.7 ± 0.10 |
98.2 ± 2.00 |
98.7 ± 2.30 |
16 |
97.1 ± 1.80 |
98.3 ± 0.80 |
102.2 ± 0.70 |
101. ± 0.10 |
100.3 ± 0.70 |
100.5 ± 0.60 |
17 |
98.6 ± 0.04 |
99.8 ± 0.30 |
99.8 ± 1.40 |
99.6 ± 0.30 |
98.9 ± 0.70 |
98.5 ± 0.40 |
18 |
98.4 ± 0.00 |
97.3 ± 1.50 |
99.7 ± 0.05 |
98.6 ± 0.50 |
98.7 ± 0.30 |
99.5 ± 0.19 |
19 |
99.1 ± 1.09 |
99.2 ± 0.21 |
99.4 ± 1.60 |
98.9 ± 0.40 |
94.1 ± 1.30 |
94.8 ± 1.60 |
20 |
102.0 ± 3.00 |
98.0 ± 1.02 |
101.4 ± 0.30 |
99.4 ± 1.00 |
100.0 ± 4.00 |
94.2 ± 0.12 |
21 |
97.0 ± 6.00 |
99.6 ± 1.50 |
99.8 ± 1.40 |
99.6 ± 0.30 |
98.6 ± 1.70 |
97.9 ± 1.30 |
22 |
100.2 ± 0.30 |
99.4 ± 2.00 |
98.0 ± 40 |
101.0 ± 4.0 |
96.0 ± 3.00 |
98.9 ± 1.08 |
23 |
95.1 ± 1.20 |
99.7 ± 1.50 |
99.4 ± 0.06 |
99.9 ± 0.30 |
99.9 ± 1.30 |
97.8 ± 0.70 |
24 |
100.6 ± 0.05 |
99.6 ± 1.20 |
99.4 ± 0.17 |
99.9 ± 0.20 |
98.0 ± 4.00 |
95.5 ± 0.40 |
|
FOS: Fosaprepitant
DEX: Dexamethasone
GRA: Granisetron
%RC: Percentage of remaining drug concentration (%)
t7: 7 days of storage
t15: 15 days of storage |
Table 9: Percentage of remaining concentrations of FDG in mixtures at day 7 and 15 of storage. |