| |
Nominal Concentration |
Calculated Concentrations |
Between-run accuracy and Precision |
| Run 1 |
Run 2 |
Run 3 |
mean |
RE% |
RSD% |
| Morphine |
|
|
|
|
3.994 |
-0.1% |
0.7% |
| QC1 |
4.0 mg/mL |
3.966 |
3.997 |
3.999 |
| QC2 |
4.012 |
3.976 |
4.015 |
| QC3 |
4.026 |
3.973 |
3.973 |
| QC4 |
3.954 |
4.002 |
3.940 |
| QC5 |
3.993 |
4.033 |
4.028 |
| QC6 |
4.035 |
3.985 |
3.986 |
| Within-run mean |
3.998 |
3.994 |
3.990 |
| Within-run RE% mean |
|
-0.1% |
-0.1% |
-0.2% |
|
|
|
| Within-run CV% |
|
0.8% |
0.6% |
0.8% |
|
|
|
| Ropivacaïne |
|
|
|
|
|
|
|
| QC1 |
8.0 mg/mL |
7.905 |
7.844 |
7.935 |
7.937 |
-0.8% |
0.9% |
| QC2 |
7.971 |
7.859 |
8.037 |
| QC3 |
7.965 |
7.858 |
7.978 |
| QC4 |
7.859 |
7.834 |
7.994 |
| QC5 |
7.994 |
7.946 |
7.962 |
| QC6 |
7.988 |
7.874 |
8.063 |
| Within-run mean |
7.947 |
7.869 |
7.995 |
| Within-run RE% mean |
|
-0.7% |
-1.6% |
-0.1% |
| Within-run RSD% |
|
0.7% |
0.5% |
0.6% |
|
|
|
| Ziconotide |
|
|
|
|
|
|
|
| QC1 |
1.0 μg/mL |
1.021 |
0.987 |
0.879 |
0.985 |
-1.5% |
5.0% |
| QC2 |
1.065 |
1.003 |
0.921 |
| QC3 |
1.073 |
0.993 |
0.941 |
| QC4 |
1.026 |
1.012 |
0.948 |
| QC5 |
0.981 |
0.999 |
0.949 |
| QC6 |
0.978 |
1.010 |
0.943 |
| Within-run mean |
1.024 |
1.001 |
0.930 |
| Within-run RE% mean |
|
2.4% |
0.1% |
-7.0% |
| Within-run RSD% |
|
3.9% |
1.0% |
2.9% |
|
|
|
|
