| |
LVP
(mmHg) |
LVEDP
(mmHg) |
Tau
(ms) |
PHT
(ms) |
Heart rate
(min-1) |
| SD |
|
|
|
|
|
| Dob 1 |
160±14 |
4±1 |
19±1 |
11±2 |
359±11 |
| Dob 2 |
176±15 |
3±1 |
19±2 |
9±1 |
380±13 |
| Dob 3 |
206±19 |
4±0.4 |
18±1 |
9±1 |
391±13 |
| STZ 2 weeks |
|
|
|
|
|
| Dob 1 |
115±7* |
12±1* |
19±1 |
12±1 |
271±9* |
| Dob 2 |
136±10* |
11±2* |
21±3 |
13±1 |
293±10* |
| Dob 3 |
135±8* |
11±1* |
21±2 |
13±1 |
305±7* |
| STZ 6 weeks |
|
|
|
|
|
| Dob 1 |
94±5* |
7±1 |
19±1 |
12±0.3 |
240±8* |
| Dob 2 |
102±5* |
6±1 |
19±2 |
12±1 |
254±7* |
| Dob 3 |
107±5* |
6±1 |
21±3 |
13±1 |
269±7* |
*=P<0.05 vs. SD, #=P<0.05 vs. SD and STZ 2 weeks. SD = Sprague Dawley, STZ = Streptozotozin |
