Figure 4: Serial LV ejection fraction (LVEF) monitored by echocardiography. Full normalization of LVEF occurred eight months post-discharge. Incremental doses of chemotherapy was re-instituted with 3 cycles of rituximab followed by 2 cycles of reduced R-CHOP doses (see Table 1 for specific dosing) and 3 cycles of full R-CHOP doses. R-CHOP: Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone combination.