Figure 1: Time course of changes in creatine phosphokinase and myokine levels after exercise. Healthy volunteers (n=9) were made to exercise at 85% of the target heart rate for 30 minutes. Plasma levels of creatine phosphokinase (panel A), interleukin-6 (panel B) and FGF21 (panel C) were measured. : P<0.001, *: P<0.01 versus before exercise.