Figure 1: Coronary flow and coronary vascular resistance after 30-min hyperosmotic perfusion. Hyperosmotic NaCl perfusion (osmolarity at 320, 350 and 400 mOsm/L versus control at 300 mOsm/L) increased coronary flow (a) and reduced coronary vascular resistance (b) in both normotensive Wistar- Kyoto rats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP). n=9-10. *P<0.05, **P<0.01 versus respective controls.