Figure 5: Myocardial creatine phosphokinase (CPK) leakage and maleic dialdehyde (MDA) production after ischemia/reperfusion with and without hyperosmotic perfusion. Hyperosmotic NaCl lowered myocardial CPK leakage and MDA dose-dependently in normotensive Wistar-Kyoto r ats (WKY) and stroke-prone spontaneously hypertensive rats (SHRSP). n=7-10. *P<0.05, **P<0.01 versus respective controls.