ROC curve and Risk Analyses
Autoantibodies Prognostic Accuracies AUC 95% CI P
Anti-apoA-1 IgG, Index Anti-HSP-60 antibodies, ng/ml Anti-β2GPI IgG, units
Anti-βGPI IgM, units
Anti-βGPI IgA, units Anti-cardiolipin IgG, units
Anti-cardiolipin IgM, units
Anti-cardiolipin IgA, units Anti-β2GPI D4/5 IgA, units Anti-PC IgM, U/ml
0.65 0.58 0.54
0.51
0.53 0.58
0.59
0.54 0.55 0.52
0.53-0.76 0.48-0.69 0.43-0.65
0.40-0.63
0.42-0.64 0.47-0.69
0.48-0.70
0.42-0.66 0.45-0.65 0.37-0.59
0.007 0.06 0.23
0.41
0.29 0.08
0.05
0.27 0.16 0.37
Cox Regression analyses for MACE prediction Unadjusted Hazard Ratio P *Adjusted Hazard Ratio P
Anti-apoA-1 IgG positivity 3.92 0.001 3.80 0.002
*Adjusted for the 10-year global Framingham risk score
Table 2: