Vehicle (n=12) LPS (n=13) LPS+4F (n=12) MAP (mmHg) 94 ± 2 97 ± 6 92 ± 5 Systolic BP (mmHg) 114 ± 2 116 ± 5 110 ± 5 Diastolic BP (mmHg) 75 ± 2 76 ± 5 73 ± 4 HR (beats/min) 340 ± 5 382 ± 13 * 378 ± 9 * LVEDP (mmHg) 6 ± 1 2 ± 1 * 4 ± 1 *,# LVESP (mmHg) 70 ± 3 64 ± 3 64 ± 3 Heart wet-dry weight ratio 3.38 ± 0.05 3.77 ± 0.14 * 3.48 ± 0.04#

Table 2: Pressure measurements in control, LPS and LPS+4F treated rats. Data were obtained 24 hrs post treatment and are means ± SEM. * (P < 0.05) denotes a significant difference compared to vehicle treated rats. # (P < 0.05) denotes a significant difference compared to LPS-treated rats.