Variable

HOMA2-IR >2.2 (140 patients)

HOMA2-IR ≤2 (378 patients)

OR (CI)

P

Anthropometric Parameters
Male
Aged (m ± sd)
BMI (kg/m2)
BMI > 30 (kg/m2)

74%
66 ± 12
29 ± 4
32%

77%
64 ± 13
 27 ± 4
21%

0.8 (0.6-1.2)
1.5 (1-2)

0.4
0,13
0,001
0.03
Previous Disorders
NYHA>2
Diabetes
Hypertension
Previous Myocardial Infarction
Current smoker
Dyslipemia
Chronic Renal Disease
Metabolic Syndrome

11%
48%
73%
31%
32%
54%
19%
71%

3%
29%
60%
21%
42%
52%
6%
39%

2.4 (1.6-3.5)
1.8 (1.3-2.4)
1.5 (1.1-2.2)
1.4 (1-1.9)
0.7 (0.5-1)
1 (0.78-1.4)
1.5 (0.9-2.4)
2.7 (2-3.7)

0.001
0.001
0.012
0.05
0.045
0.66
0.12
<0.001
Acute Myocardial Infarction
Killip>1 (admission)
Left Ventricular EF (243 patients)
Percutaneous Coronary Intervention
Coronary Artery Affected>1
Coronary Artery Disease
CK-MB (m ± st. error mean)
In-Hospital Mortality
In-Hospital Stay (m ± sd)

43%
48 ± 15
88.3%
50%
1.9 ± 1
138 ± 15
15.5%
11.8 ± 9

24%
53 ± 11
88%
31%
1.4 ± 0.8
132 ± 8
2.5%
9.8 ± 6
0.8 (0.6-1.1)
1.8 (1.3-2.5)
1 (0.66-1.5)
2.8 (2.1-3.7)
2.8 (2-3.8)

<0.001
0.020
0.99
0.001
<0.001
0.7
<0.001
0.023
Metabolic and Inflammatory parameters
Glycemia  (mg/dL) (admission)
Fasting Glycemia (mg/dL)
HbA1c (%)
Insulin (mU/ml)
C-peptide (ng/ml)
Triglyceride (mg/dL)
Triglyceride > 150 mg/dL
Cholesterol (mg/dL)
HDL (mg/dL)
LDL (mg/dL)
Creatine (mg/dl)(admission)
Albuminuria/creatinuria*
Albuminuria >20 mg/dL
CRP (admission)(mg/L)*
WBC (admission)(109/L)


193 ± 87
160 ± 64
6.7 ± 1.4
29 ± 24
5.4 ± 4
166 ± 88
42%
180 ± 52
42 ± 15
112 ± 51
1.38 ± 1.2
96 ± 16
67%
29 ± 4
11,176 ± 3,702


156 ± 68
115 ± 37
6 ± 1.2
8 ± 8
3 ± 1.3
135 ± 84
28%
177 ± 46
43 ± 11
111 ± 40
1.1 ± 0.7
62 ± 8
42%
25 ± 2
11,355 ± 8,54
1.56 (1.15-2)
2.2 (1.5-3)


<0.001
<0.001
<0.001
<0.001
<0.001
<0.001
0.004
0.6
0.3
0.8
0.04
0.001
<0.001
0.4
0.5
Pharmacologic Treatment
Aspirin
Clopidogrel
Heparin
Β-Blockers
ACE inhibitors
Statin
Diuretics
Inotropic agents
Insulin (163 patients) (35%)

96%
84%
85%
32%
60%
87%
43%
17%
52%

96%
88%
80%
31%
61%
91%
26%
6%
29%

1 (0.47-2.2)
0.78 (0.5-1.1)
1.3 (0.8-2)
1 (0.4-1.2)
0.89 (0.6-1.2)
0.7(0.48-1.1)
1.7 (1.2-2.3)
2 (1.4-2.9)
1.9 (1.4-2.6)

0.94
0.26
0.23
0.6
0.46
0.21
0.001
0.001
0.001
NYHA: New York Heart Association. STEMI: ST elevation myocardial infarction. CK-MB: Creatine Kinase MB. HDL: High Density Lipoprotein. LDL: Low Density Lipoprotein. PCI: Percutaneous Coronary Intervention. CRP: C-Reactive Protein. WBC: White Blood Cell
Table 1: Acute myocardial infarction: Clinical, hemodynamic and metabolic characteristics of the study population according to HOMA2-IR.