| Gene ontology |
Gene full name/Function |
Gene symbol
(fold-change and p-value) |
| ECM proteolytic activity, Collagen formation & focal adhesion |
collagen, procollagen C-endopeptidase enhancer, Lysis oxidase, collagen triple helix repeat containing 1, fibrillin, fibronectin, versican, hyaluronic acid (HA) receptor, Metalloproteinase, EGF containing fibulin-like extracellular matrix protein 2, elastin, spondin 1, extracellular matrix protein, lumican, fibroblast growth factor 9, Tissue growth factor, periostinosteoblast specific factor |
Col1a1 (5.36, 0.0001), Col5a1 (3.65, 0.0006), Col5a2 (4.84, 0.0004), Col4a1 (3.61, 0.01), Col6a3 (3.64, 0.01), Col1a2 (4.20, 0.0003), Col3a1 (4.08, 0.0006), Pcolce (4.05, 0.003), Loxl1 (3.27, 0.0037), Cthrc1 (6.17, 0.0005), Fbn1 (4.45, 0.0002), Fn1 (4.83, 0.0005), Vcan (3.63, 0.0001), CD44 (1.83, 0.0031), MMP14 (3.82, 0.0012), MMP19 (2.19, 0.0011), MMP23 (2.38, 0.0022), Timp1 (7.40, 0.0049), Efemp2 (3.36, 0.0031), Eln (3,21, 0.0016), Spon1 (3.37, 0.0007), Lum (2.57, 0.0179), FGF9 (-1.61, 0.0414), CTGF (3.07, 0.0015), TGFb1 (1.50, 0.0315), Postn (14.94, 0.00001) |
| Complement Cascades & Immune response |
Complement factor, Integrin alpha, leukocyte immunoglobulin-like receptor, Fc fragment of IgG, colony stimulating factor 2 receptor, beta |
C3ar1 (2.75, 0.0028), C3 (4.13, 0.0164), C6 (2.99, 0.0112), C1r (2.08, 0.0193), C2 ( 2.72, 0.0410), Itgam (3.82, 0.001), Lilrb4 (3.20, 0.0009), Fcgr1a (3.23, 0.0029), Csf2rb (3.33, 0.0124) |
| Blood vessel formation & angiogenesis |
tubulin, beta 6, Heme oxigenase, Cys-rich angiogenic inducer 61, alanyl aminopeptidase |
Tubb6 (3.29, 0.0076), Hmox1 (6.99, 0.0001), Cyr61 (3.30, 0.0283), Anpep (4.05, 0.0003) |
| Muscle contraction & Ca2+ signal |
tropomyosin 1, regulates ca-dep interaction of actin- myosin, Myoferlin, Myoferlin |
Tpm2 (3.60, 0.0035), MyoF (2.26, 0.0059), Myo1f (2.80, 0.0070) |
| Lipid |
Phospholipase A2 |
Pla2g2a (2.53, 0.0084), Pla2g15 (1.77, 0.0075) |
|
Cell cycle arrest & apoptosis |
FBJ osteosarcoma viral oncogene homolog, pleiomorphic adenoma gene-like 1, lipocalin 2, lysozyme |
fos (1.77, 0.0178), Plagl1 (3.49, 0.038), Lcn2 (4.14, 0.0029), Lyz2 (2.74, 0.0338) |
| Protein trafficking & phagosomal |
RAS oncogene family, lysosomal/endosomal-associated membrane glycoprotein |
Rab13 (1.90, 0.011), Rab32 (2.07, 0.0011), CD68 (3.69, 0.0003) |
| Metabolism |
glutathione peroxidase 7, pyruvate dehydrogenase kinase, isozyme 2, hemochromatosis type 2, heat shock 70kDa protein 4-like, protein folding |
Gpx7 (3.34, 0.0174), Pdk2 (-1.97, 0.0267), Hfe2 (-2.14, 0.026), Hspa4l (-1.67, 0.0365) |
| Mitochondrial activity |
cytochrome b-245, NADH dehydrogenase (ubiquinone), GrpE-like 1, mitochondrial |
Cybb (3.12, 0.0023), Ndufs4 (-2.26, 0.0157), Grpel1 (-1.69, 0.0274) |
| Fatty acid & cholesterol catabolism |
peroxisomal membrane protein 2, apolipoprotein E |
Pxmp2 (-1.77, 0.0347), ApoE (1.66, 0.0054) |
| Glucose transport |
HtrA serine peptidase,may regulate insulin-likeGFs availability, insulin |
Htra1 (3.36, 0.0244), Ins1 (-1.67, 0.0441) |
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