| Gene Ontology |
Gene Function |
Gene Symbols
(Fold-change STN vs Sham, p-value) |
| Ribosome biogenesis & translational elongation |
ribosomal protein small subunits and basic leucine zipper, translational initiation |
Rps14 (1.66, 0.018), Rps23 (1.73, 0.017), Rps19 (1.58, 0.030), Rps11 (1.61, 0.0187), Rps18 (1.52, 0.0243), Rps24 (1.61, 0.0441), Rps2-ps5(1.50, 0.0118 ), Rpl24 (1.52, 0.0484), Rpl37a (1.57, 0.0338), Rpl35a (1.5, 0.033),Bzw1 (-1.62, 0 .043) |
| Nucleosome assembly |
histone 1 and histone 3 |
hist1h2bm (1.95, 0.045), hist1h2bf (1.54, 0.0331), hist3h2bb (1.64, 0.0355) |
| Ubiquitine-dependent proteolysis & catalytic actibity |
proteasome subunit, ubiquitin specific protease, ubiquitin-fold modifier conjugating enzyme, RAS oncogene, may be involved in phagosome maturation, adaptor-related protein,protein lysosome targeting, N-glycanase (proteosome degradation of misfolded proteins), WAP four-disulfide core domain 2, protease inhibitor, phosphotriesterase related, catabolism |
Psma3 (-1.52, 0.0152), Psma4 (-1.66, 0.0236), Psmd6 (-1.68, 0.0297), Usp16 (-1.52, 0.0484), Usp14 (-1.59, 0.0395), Ufc1 (-1.68, 0.0472), Rab14 (-2.12, 0.024), Rab2a (-1.73, 0.0263), Rab11a (-1.67, 0.0275), Rabif (1.59, 0.0299), Ap3m1(-1.98, 0.0198), Ngly1 (-1.56, 0.0272),Wfdc2 (-3.13, 0.0433), Pter (-1,54, 0.0467) |
| Lipid catabolism |
phospholipase A2 |
Pla2g4c (-1.13, 0.0287 |
| Proteolysis |
mast cell protease, may be involved in cardiac hypertrophy |
MCPT2 (-4.39, 0.0729*) |
| ER- Golgy transport |
syntaxin, Golgi & post Golgy transport, endoplasmic reticulum aminopeptidase, vacuolar protein sorting 29, lectin, mannose-binding, involved in ER to Golgi transport |
Stx7 (-1.86, 0.0333), Erap1 (-1.52, 0.0472), Vps29 (-1.88, 0.0348, Lman1 (-1.60, 0.0256) |
| Apoptosis |
BCL2-like 13 (apoptosis facilitator), epithelial membrane protein 2 |
Bcl2l13 (-1.63, 0.0157), Emp2 (-2.18, 0.0491) |
| Inflammation |
interleukin 13 receptor, lymphocyte antigen 6 |
Il13ra1 (-1.70, 0.0267), Ly6al (-1.98, 0.0518) |
| Transcriptional regulation & RNA processing |
MAX interactor, myc transcriptional repressor, COMM domain, transcription regulator, RNA terminal phosphate cyclase, Cbp/p300-interacting transactivator, transcription coactivator |
Mxi1 (-1.85, 0.0227), Commd3 (-2.01, 0.0231), Rtcd1 (-1.52, 0.0278), Cited4 (-1.73, 0.0480) |
| Protein folding |
chaperonin containing TCP1, unfolded protein binding, t-complex, chaperon for actin & tubulin |
Cct8 (-1.53, 0.0134), Tcp1 (-1.72, 0.0158) |
| Ca2+-binding & cardiac contraction |
scinderin, Ca(2+)-dependent actin-severing and -capping, calcium binding protein |
Scin (-3.27, 0.0363), Chp (-1.57, 0.0255) |
| Adhesion, differentiation & cell growth |
intercellular adhesion molecule 1, thioredoxin domain, acossiated with cell differentiation, secretoglobin, negative regulator of cell growth, ectonucleotide pyrophosphatase/phosphodiesterase 3 |
Icam1 (-1.51, 0.0358), Txndc9 (-1.61, 0.0323), scgb3a1 (-13.86, 0.0326), Enpp3 (-1.95, 0.0367) |
| Oxidation-reduction |
selenoprotein, may be involved in oxidation-reduction reacts, isocitrate dehydrogenase 1 (NADP+) |
Sepw1 (1.61, 0.0093), Idh1 (1.61, 0.0380) |
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