Gene Ontology |
Gene Function |
Gene Symbols
(Fold-change and p-value) |
Differentiation |
notch 3, may be involved in cardiomyocyte differentiation, presenilin enhancer 2 homolog, required for the Notch signaling pathway |
Notch3 (3.11, 0.0345), Psenen (-1.81, 0.0170) |
Coenzyme Q biosynthesis |
cytochrome c oxidase, coenzyme, required for Ubiquinone (coenzyme Q) biosynthesis, coenzyme |
Cox18 (-2.04, 0.0036), Coq3 (-1.77, 0.0129), Coq7 (-1.74, 0.0063), Coq2* (-1.60, 0.057), Coq6 (-1.67, 0.026), Coq10a (-1.55, 0.013) |
ECM proteolysis |
matrix metallopeptidase 12, may have a role in glomerular injury, Disintegrin and metalloproteinase domain 12, ADAMTS-like 2 |
MMP12 (3.95, 0.0443), Adam12 (2.39, 0.0083), Adamtsl2 (1.66, 0.0073) |
Cell migration |
hyaluronan synthase |
has1 (2.03, 0.0337) |
Cell growth and proliferation |
latent transforming growth factor beta binding protein 2, transforming growth factor b, early growth response 1, transcription, cyclin-dependent kinase 1, cyclin L2, EGF-like-domain, NDRG family member 3, negative regulation of cell growth |
Ltbp2 (3.61, 0.001), TGFb1 (1.68, 0.0195), Egr1 (2.57, 0.0050), CDC2 (1.65, 0.0207), Ccnl2 (2.03, 0.0085), Egfl6 (-1.87, 0.0327), Ndrg3 (-1.80, 0.0091) |
Ca-binding |
transient receptor potential cation channel, subfamily V, member 2, two pore segment channel 1, Ca- channel activity |
TRPV2 (1.66, 0.0035), Tpcn2 (1.56, 0.0341) |
Transcription factors |
nuclear transcription factor, nuclear receptor corepressor 2, transcriptional silencing, runt-related transcription factor |
Nfxl1 (1.69, 0.0159), Ncor2 (1.51, 0.0209), Runx1 (2.13, 0.0314) |
Proteolysis |
mast cell protease 1, mast cell protease 10, mast cell protease 8 |
Mcpt1 (-2.20, 0.0495), Mcp10 (-1.87, 0.0221), Mcpt8 (-1.65, 0.0284) |
Phagosome maturation |
member RAS oncogene family |
Rab20 (-2.09, 0.017), Rab27a (-1.61, 0.003) |
Inflammation |
interleukin 33, interleukin 17, interleukin 10 |
Il33 (-1.99, 0.0412), Il17ra (1.84, 0.0125), Il10ra (1.73, 0.0203) |
Macromolecule metabolism
Ribosome |
aldehyde dehydrogenase 3 family, alcohol dehydrogenase 1A |
Aldh3a1 (-1.61, 0.0135), Aldh3a2 (-1.53, 0.0273), Adh1 (-1.77, 0.0367) |
Ribosome |
ribosomal protein, exosome component 5, ribosome biogenesis |
Rpl3 (1.88, 0.0254), Exosc5 (-1.57, 0.0481) |
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