Medication at 90 min after furosemide The rats were monitored throughout the 60 min after medication application Number of premature ventricular beats (per min), Mean±S.D. Duration of ventricular tachycardia (min), Mean±S.D. Duration of third-degree AV block (min), Mean±S.D. Absolute termination of arrhythmias (min.), Mean±S.D. Time till fatal outcome (min.), Mean±S.D. Mortality rate (surviving/dead rats) CONTROL(saline 5ml/kg i.p.) 104.1±3.6 8.3±2.1 6.8±1.5 Not determined 55.6±3.8 0/10 BPC 10μg/kg i.p. 14.6±4.9 † 0.5±0.1 † 0.6±0.2 † 4.9±0.1 † Not determined 10/0 † BPC 10ng/kg i.p. 18.2±3.2 † 0.8±0.1† 1.0±0.3† 7.9±0.2 † Not determined 10/0 † CONTROL(saline 5ml/kg i.g.) 106.3±2.9 11.3±3.6 9.6±2.1 Not determined 52.9±5.9 0/10 BPC 10μg/kg i.g. 19.2±3.9 † 0.8±0.4 † 0.8±1.1† 8.9±0.2 † Not determined 10/0 † BPC 10ng/kg i.g. 25.7±4.2 † 1.1±0.6 † 1.2±0.8 † 11.2±0.3† Not determined 10/0†

Table 6: When hypokalemia- third-degree AV block and ventricular tachycardia were already established, rats were monitored throughout the 60 min after application BPC 157 (intraperitoneally or intragastrically) as a therapy at 90 min after furosemide for a number of premature ventricular beats (per min), duration of ventricular tachycardia (min), duration of third-degree AV block (min), absolute termination of arrhythmias (min.), time till fatal outcome (min.), mortality rate (surviving/dead rats). Values are mean ± SEM. †P<0.05 significantly different from control values.