| |
Non-high IL-6 group
(<2.6 pg/mL) (n=41) |
High IL-6 group
(>2.6 pg/mL) (n=41) |
P |
| Female/male |
14 / 27 |
19 / 22 |
0.368 |
| Age (years) |
59±12 |
61±12 |
0.566 |
| Current smoker (%) |
58.5 |
43.9 |
0.269 |
| Hypertension (%) |
53.6 |
73.2 |
0.108 |
| Dyslipidemia (%) |
73.2 |
87.8 |
0.162 |
| Drug use (%) |
|
|
|
| Statin |
36.6 |
48.8 |
0.372 |
| Ca channel antagonist |
34.1 |
48.8 |
0.262 |
| ACE inhibitor / ARB |
26.8 |
39.0 |
0.347 |
| α blocker |
7.3 |
0 |
0.241 |
| BMI (kg/m2) |
23.9±5.3 |
26.8±5.4 |
0.015* |
| Systolic BP (mmHg) |
129±23 |
130±21 |
0.956 |
| Diastolic BP (mmHg) |
71±14 |
68±14 |
0.298 |
| Duration of diabetes (years) |
7.95±7.27 |
11.95±9.53 |
0.036* |
| Fasting plasma glucose (mg/dL) |
156±49 |
146±41 |
0.318 |
| Fasting IRI (μU/mL) |
8.33±5.36 |
11.32±7.63 |
0.437 |
| HOMA-R |
3.13±2.23 |
4.04±2.87 |
0.115 |
| HbA1c (%) |
8.89±1.89 |
8.18±1.42 |
0.057 |
| Triglycerides (mg/dL) |
136±83 |
185±216 |
0.180 |
| HDL cholesterol (mg/dL) |
45.9±13.2 |
45.9±15.3 |
0.985 |
| LDL cholesterol (mg/dL) |
117±28 |
123±40 |
0.460 |
| Uric acid (mg/dL) |
5.24±1.64 |
5.84±1.68 |
0.104 |
| Creatinine clearance (mL/min) |
114.3±43.0 |
97.1±43.5 |
0.076 |
| IL-6 (pg/mL) |
1.59±0.55 |
6.33±4.60 |
<0.001** |
Data are mean ± SD. ACE, angiotensin-converting enzyme; ARBs, angiotensin II
receptor blockers; BMI, body mass index; BP, blood pressure; HDL, high-density
lipoprotein; HOMA-R, homeostasis model assessment ratio; IL-6, interleukin-6; IRI,
immunoreactive insulin; LDL, low-density lipoprotein. *p<0.05, **p<0.01 |
