Figure 2: Typical macroscopic examples of left ventricular hypertrophy and remodeling in specific groups. Representative midventricular sections of the left ventricle stained with trichrome-Masson are shown. ShamC: control sham group, ShamM: metformin-treated sham group, ARC: untreated AR group and ARM: metformin-treated AR group. Scale bar at the bottom right of the figure: 1cm.