Characteristics of an ideal cardiac biomarker
High sensitivity
High concentration in myocardium after myocardial injury
Rapid release for early diagnosis
Long half-life in blood for late diagnosis
High specificity
Absent in non-myocardial tissues
Not detectable in blood of non-diseased subjects
Analytical characteristics
Measurable by cost-effective assay
Simple to perform
Rapid turnaround time
Sufficient precision and trueness
Clinical characteristics
Ability to influence therapy
Ability to improve patient outcome
Table 1: Characteristics of an ideal cardiac biomarker.