Characteristics of an ideal cardiac biomarker |
High sensitivity |
High concentration in myocardium after myocardial injury |
Rapid release for early diagnosis |
Long half-life in blood for late diagnosis |
|
High specificity |
Absent in non-myocardial tissues |
Not detectable in blood of non-diseased subjects |
|
Analytical characteristics |
Measurable by cost-effective assay |
Simple to perform |
Rapid turnaround time |
Sufficient precision and trueness |
|
Clinical characteristics |
Ability to influence therapy |
Ability to improve patient outcome |