Group |
TNF-α(pg/ml) |
hsCRP(mg/l) |
I |
Normal group |
Zero time |
0.60 ± 0.09 |
3.0 ± 0.0 |
6 weeks |
1.08 ± 0.11 |
3.0 ± 0.0 |
12 weeks |
1.05 ± 0.06 |
3.0 ± 0.0 |
II |
Induced untreated group |
Zero time |
0.77 ± 0.10 |
3.0 ± 0.0 |
6 weeks |
4.70 ± 0.54* |
43 ± 1.8* |
12 weeks |
7.05 ± 0.44† |
57 ± 3.0† |
III |
vildagliptin treated group |
Zero time |
0.85 ± 0.05 |
3.0 ± 0.0 |
6 weeks |
4.60 ± 0.15* |
41 ± 1.8* |
12 weeks |
2.70 ± 0.17† |
19 ± 1.0† |
* P < 0.05(means at 6 weeks versus means at zero time)
† P < 0.05(means at 12 weeks versus means at 6 weeks |