| |
ALL PATIENTS n=80 |
USUAL CARE n=40 |
INTEGRATED MANAGEMENT n = 40 |
P χ2/t test |
| Age |
72 ± 3 |
73 ± 5 |
71 ± 4 |
|
| Males / Females |
59 / 22 |
29 / 18 |
30 / 4 |
NS |
| Ischemic Heart Disease (%) |
44 (54.3%) |
26 |
17 |
NS |
| Diabetes (%) |
38 (46.9%) |
20 |
18 |
NS |
| Familiar history of IHD (%) |
33 (40.0%) |
18 |
15 |
NS |
| Smokers (%) |
48 (59.3) |
26 |
22 |
NS |
| Hypercholesterolemia (%) |
22 (27.2%) |
14 |
8 |
NS |
| NO RISK FACTORS (%) |
9 (11%) |
5 (12%) |
4 (10%) |
NS |
| 1 risk factor (%) |
12 (15%) |
8 (20%) |
4 (10%) |
NS |
| 2-3 risk factor (%) |
26 (32%) |
15 (38%) |
11 (28%) |
NS |
| > 3 risk factor (%) |
34 (43%) |
19 (48%) |
15 (38%) |
NS |
| SAP mmHg |
123 ± 11 |
127 ± 10 |
119 ± 12 |
NS |
| DAP mmHg |
75 ± 9 |
79±8 |
70 ± 11 |
NS |
| HR b/min |
67 ± 5 |
67±4 |
67 ± 6 |
NS |
| BMI Kg/m2 |
26.8 ± 1.0 |
27.3 ±1.1 |
26.2 ± 0.8 |
NS |
| NYHA class |
3.01 ± 0.45 |
2.90 ± 0.69 |
3.08 ± 0.57 |
0.33 |
| ECHOCARDIOGRAM |
|
|
|
|
| EF (%) |
32 ± 5 |
32 ± 8 |
31 ± 6 |
0.31 |
| PAP (mmHg) |
40 ± 8 |
39 ± 9 |
41 ± 13 |
0.48 |
| Diastolic dysfunction (%) |
35 (43%) |
16 (40%) |
19 (47%) |
NS |
| Moderate/severe MR (%) |
29 (36%) |
15 (39%) |
13 (33%) |
NS |
| BLOOD TESTS |
|
|
|
|
| K+ (mEq/l) |
4.40 ± 0.5 |
4.34 ± 0.6 |
4.42 ± 0.7 |
NS |
| Na+ (mEq/l) |
142 ± 2.3 |
142 ± 3.6 |
142 ± 4.1 |
NS |
| Glucose (mg/dl) |
101 ± 6 |
102 ± 8 |
100 ± 7 |
NS |
| Hemoglobin (g/dl) |
12.94 ± 1.3 |
12.46 ± 1.5 |
13.35 ± 1.3 |
NS |
| Serum creatinine (mg/dl) |
1.32 ± 0.6 |
1.22 ± 0.5 |
1.37 ± 0.5 |
NS |
| BNP (pg/ml) |
332 ± 93 |
361 ± 72 |
314 ± 94 |
p=0.59 |
| PSYCHOLOGICAL TESTS |
|
|
|
|
| STAI-6 |
41.8 ± 7.4 |
41.5 ± 6.6 |
42.2 ± 8.2 |
NS |
| PHQ-9 |
25.9 ± 3.4 |
25.0 ± 3.3 |
26.8 ± 3.3 |
NS |
| PGWBI |
61.4 ± 8.3 |
62.1 ± 8.7 |
60.6 ± 7.8 |
NS |
| MMAS |
2.7 ± 0.5 |
2.7 ± 0.9 |
2.8 ± 0.4 |
NS |
|
| SAP: systolic arterial pressure; DAP: diastolic arterial pressure; HR: heart rate;
EF: ejection fraction; PAP: pulmonary artery pressure (estimated); MR: mitral
regurgitation; BNP: Brain Natriuretic Peptide; STAI-6: Spielberger’s State Trait
Anxiety Inventory; PHQ-9: Patient Health Questionnaire for depression; PGWBI:
Perceived General Well Being Index; MMAS: Morisky Medical Adherence scale |
| Table 2: Patients’ Characteristics at Enrolment. |
