| |
USUAL CAREn = 40 |
INTEGRATED MANAGEMENT n = 40 |
PANOVA/χ2 |
| |
T0 baseline |
T4 followup |
T0 baseline |
T4 followup |
UC - IM |
| NYHA class |
2.90±0.69 |
2.40±0.45 * |
3.08±0.57 |
2.08±0.38 * |
<0.02 |
| ECHOCARDIOGRAM |
|
|
|
|
|
| EF (%) |
32 ± 8 |
34 ± 10 |
31 ± 6 |
36 ± 9 * |
0.063 |
| PAP (mmHg) |
39 ± 9 |
38 ± 10 |
41 ± 13 |
33 ± 8 * |
<0.05 |
| Diastolic dysfunction (%) |
16 (40%) |
14 (33%) |
19 (47%) |
10 (25%) * |
0.081 |
| Moderate/severe MR (%) |
15 (39%) |
15 (39%) |
13 (33%) |
12 (30%) |
0.121 |
| BLOOD TESTS |
|
|
|
|
|
| BNP (pg/ml) |
361 ± 72 |
263 ± 152 |
314 ± 94 |
202 ± 127* |
0.058 |
| PSYCHOLOGICAL TESTS |
|
|
|
|
|
| STAI-6 |
41.5 ± 6.6 |
41.6 ± 6.0 |
42.2 ± 8.2 |
35.1± 6.3 § |
< 0.01 |
| PHQ-9 |
25.03 ± 3.3 |
29.1 ± 3.3 * |
26.8 ± 3.3 |
24.0 ± 2.6 § |
< 0.01 |
| PGWBI |
62.1 ± 8.7 |
56.2± 8.7 * |
60.6 ± 7.8 |
68.3 ± 3.2 § |
< 0.01 |
| MMAS |
2.7 ± 0.9 |
3.0 ± 0.8 |
2.8 ± 0.4 |
3.8 ± 0.5 * |
<0.05 |
*=p<0.05 T4 vs.T0 (T-test); §=p<0.0001 T4 vs.T0 (T-test) |
