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Figure 1: Hematoxylin and eosin stained cross sections of rabbit aorta at sites of stent implant at 4 weeks follow up. Marked inflammatory plaque is detected with saline treatment 4 weeks after balloon angioplasty and stent implant. M-T7 and Serp-1 markedly reduce visible plaque in cross sections at 4 weeks follow up. Saline treated rabbit with 11 daily injections - A - Mag 100X, B - Mag 400X. M-T7 treated rabbits with 11 daily injections - C - Mag 100X, D - Mag 400X. Serp-1 treated rabbits with 11 daily injections - E - Mag 100X, F - Mag 400X. |