Figure 3: Effect of T3 and T4 on HMVEC-C capillary network formation. HMVEC-C were plated on Matrigel in the absence (C) or presence of T3 (1 μM) and T4 (0.1 μM). VEGF (1 μM) was assayed as positive control. HMVEC-C were also treated with Tetrac (T) (5 μM). The histogram represents the mean value ± SD (seven microscopic fields) of network density. * p<0.05, **p<0.01 treated cells with respect to control cells: §p<0.05, §§p<0.01: cells (C, T3, T4 or VEGF) with Tetrac vs the corresponding cells without Tetrac.