Series Groups n, underwent surgery n, used for analysis m0 m21* p m0 vs m21 LVind RVind 60 min MI+Saline 48 9 396 ± 49 450 ± 49 <0.05 1.95 ± 0.13* 0.56 ± 0.08* MI+CoQ10 12 404 ± 38 455 ± 36 <0.05 2.07 ± 0.17* 0.52 ± 0.13* Sham+Saline 10 386 ± 35 448 ± 35 <0.05 1.8 ± 0.13 0.46 ± 0.08 180 min MI+Saline 32 9 330 ± 33 368 ± 38 <0.05 2.26 ± 0.24* 0.62 ± 0.12* MI+CoQ10 8 323 ± 16 362 ± 19 <0.05 2.28 ± 0.17* 0.55 ± 009† Sham+Saline 7 324 ± 31 364 ± 34 <0.05 2.09 ± 0.12 0.50 ± 0.04 LVind, LV index of hypertrophy (LV weight/rat weight); m0, rat mass at the start of experiment; m21, rat mass on day 21; RVind, RV index of hypertrophy (RV weight/rat weight). In each series there was no difference in body weight between groups on day 1 of the experiment; 21 days after surgery, rat weights were higher than initially, but without statistical significance between groups. *p < 0.05 vs. sham+Saline †p < 0.05 vs. MI+saline Statistical differences should be considered only between groups within separate 60-min or 180-min series.

Table 1: Experimental groups of rats for CoQ10 cardioprotective efficacy evaluation on the MI model.