Parameter Sham+Saline MI+Saline MI+CoQ10 HR, bpm 395.9 ± 43.7 368.7 ± 38.2 357.9 ± 28.2 ESV, µl 86.2 ± 4.2 158.1 ± 6.5* 109.8 ± 26.6*† EDV, µl 189 ± 9.2 282.7 ± 8.2* 224.8 ± 67.3*† ESP, mmHg 132.1 ± 6.8 135.2 ± 6 141.2 ± 17.4 EDP, mmHg 8.4 ± 1.5 13.1 ± 2.2* 7.7 ± 1.1† SV, µl 86.1 ± 5.6 54.7 ± 11.1* 76.3 ± 13.3† EF, % 52.2 ± 3.1 17.0 ± 8.0* 37.1 ± 3.7*† CO, ml/min 41.9 ± 3.8 21.7 ± 7* 33.5 ± 6† Ea, mmHg/µL 3.3 ± 2 5.9 ± 0.6* 4.1 ± 0.4† +dP/dtmax, mmHg/s   9843.4 ± 580 7264.5 ± 1851.6*   8685.9 ± 1549.5† -dP/dtmax, mmHg/s   395.9 ± 43.7 368.7 ± 38.2*   357.9 ± 28.2*† Values are expressed as mean ± standard deviation. CO, cardiac output; +dP/dtmax, maximum first derivative of change in pressure rise with respect to time; -dP/dtmax, maximum first derivative of change in pressure fall with respect to time; Ea, arterial elastance; EDP, end-diastolic pressure; EDV, end-diastolic volume; EF, ejection fraction; ESP, end-systolic pressure; ESV, end-systolic volume; HR, heart rate; MI, myocardial infarct; SV, stroke volume. *p < 0.05 vs. sham+saline †p < 0.05 vs. MI+saline

Table 2: Parameters of cardiac function in rats on the day 21 after coronary occlusion with and without CoQ10 injection at minute 60 after coronary artery occlusion.