|
|
V-C
(mm) |
Body weight
(g) |
Renal weight
(g) |
Relative kidney weight (%) |
|
Fetus |
Control |
3.222 ± 0.048 |
2.815 ±0.248 |
0.011 ± 0.002 |
0.40 ± 0.05 |
|
L-NAME |
2.972 ± 0.036* |
2.138 ± 0.267* |
0.008 ± 0.003 |
0.37 ± 0.10 |
|
SHR |
2.958 ± 0.086* |
2.092 ± 0.105* |
0.013 ± 0.002 |
0.60 ± 0.07* |
|
2-day |
Control |
4.886 ± 0.112 |
8.114 ± 0.440 |
0.062 ± 0.008 |
0.76±0.06 |
|
L-NAME |
4.370 ± 0.077* |
6.463 ± 0.312* |
0.037 ± 0.002* |
0.57 ± 0.04* |
|
SHR |
4.290 ± 0.318* |
6.550 ± 0.265* |
0.048 ± 0.009* |
0.73 ± 0.11 |
|
15-day |
Control |
6.898 ± 0.136 |
29.832 ± 1.315 |
0.170 ± 0.006 |
0.57±0.029 |
|
L-NAME |
7.466 ± 0.192* |
27.906 ± 2.424 |
0.203 ± 0.026* |
0.73±0.067* |
|
SHR |
6.198 ± 0.050* |
17.192±0.495* |
0.120 ± 0.010* |
0.70± 0.04* |
|
Values are means ± SD; n ± 5 animals per group
*P<0.05 vs. controls by one-way ANOVA followed by the multiple-comparison test |
Table 1: Vertex-coccyx (V-C) length, body and renal weights, and relative kidney weight of fetuses and newborns at 2 and 15 days from control, L-NAME and SHR mothers. |