| NOS-/- Mice |
Sites of gene deletion |
References |
| nNOS-/- |
Exon 2 (#1)
Exon 6
Exon 6 |
Cell 1993;75:1273-1286
Endocrinology 2002;143:2767-2774
PNAS 2003;100:9566-9571 |
| Renal collecting duct-specific nNOS-/- |
Exon 6 |
Hypertension 2013;62:91-98 |
| iNOS-/- |
Proximal 585 bases of promoter plus exons 1-4 (#2)
Near exons 1-5
Exons 12 and 13 and a part of exon 11 (#3)
|
Cell 1995;81:641-650
Nature 1995;375:408-411
PNAS 1995;92:10688-10692 |
| eNOS-/- |
Exons 24-26 (#4)
Exon 12 (#5)
Exons 24 and 25 |
Nature 1995;377:239-242
PNAS 1996;93:13176-13181
Circ Res 1998;82:186-194 |
| n/iNOS-/- |
#1 and #3
#1 and #2 |
Mol Reprod Dev 2003;65:175-179
PNAS 2005;102:10616-10621 |
| n/eNOS-/- |
#1 and #4
#1 and #5
#1 and #4 |
Cell 1996;87:1015-1023
Mol Reprod Dev 2003;65:175-179
PNAS 2005;102:10616-10621 |
| i/eNOS-/- |
#3 and #5
#2 and #4
|
Mol Reprod Dev 2003;65:175-179
PNAS 2005;102:10616-10621 |
| n/i/eNOS-/- |
#1, #2 and #4 |
PNAS 2005;102:10616-10621 |
NOS, Nitric Oxide Synthase; Nnos, Neuronal NOS; Inos, Inducible NOS; Enos, Endothelial NOS; NOS