General factors Males
Age 10-39 years
Posttraumatic hypovolemic state
Reduced cardiopulmonary reserve
Injury related factors Multiple fractures
Bilateral femur fractures
Femur shaft fractures
Lower extremity fractures
Traumatic fractures
Concomitant pulmonary injury
Surgery related factors Intramedullary reamed and unreamed nailing after femoral fracture
Joint replacement after femoral fracture
Bilateral procedure
Joint replacement with high volume prosthesis
Table 2: Risk factors for fat embolism syndrome [1]