| |
CIN* (%) in the placebo group (n=120) |
CIN(%) in the selenium group (n=117) |
Odds ratio (95% CI) |
P value** |
Age
> 60 years
≤ 60 years |
15 (26.8%)
8 (12.5%) |
8 (17%)
5 (7.2%) |
1.57 (0.73-3.38)
1.72 (0.59-5.01) |
0.23
0.30 |
Sex
Male
Female |
13 (20.6%)
10 (17.5%) |
7 (8.9%)
6 (16.7%) |
2.33 (1.10-5-48)
0.94 (0.31-2.85) |
0.04
0.91 |
| Smoking |
19 (16.8%) |
13 (12.3%) |
1.37 (0.71-2.63) |
0.34 |
| Hypertension |
15 (25%) |
4 (9.3%) |
2.69 (1.12-7.53) |
0.04 |
| Diabetes |
10 (27.8%) |
4 (11.4%) |
2.43 (0.84-7.03) |
0.08 |
Obesity
(BMI>30) |
2 (12.5%) |
0 |
3.62 (0.89-6.92) |
0.10 |
| Anaemia |
8 (25%) |
3 (13.6%) |
1.83 (0.55-6.15) |
0.30 |
| Hyperglycemia |
7 (17.9%) |
4 (12.9%) |
1.39 (0.45-4.32) |
0.56 |
LV dysfunction
( Ejection fraction< 50% ) |
11 (24.4%) |
2 (4.5%) |
5.38 (1.26-22.9) |
0.008 |
Contrast volume
≥300 cc
<300 cc |
6 (28.6%)
17 (17.2%) |
3 (12%)
10 (10.9%) |
1.38 (0.68-8.38)
1.58 (0.76-3.27) |
0.15
0.21 |
Type of procedure
Coronary angiography
PCI |
5 (9.6%)
18 (26.5%) |
3 (7.1%)
10 (13.3%) |
1.35 (0.34-5.31)
1.98 (1.01-3.99) |
0.66
0.04 |
*CIN is defined as a minimum 0.5 mg/dl or 25% increase in serum
creatinine above baseline 48 hours after contrast media
administration. **P value <0.05 was considered statistically significant.
LV: Left Ventricle; PCI: Percutaneous Coronary Intervention