Baseline (n=81) Follow-up(n=81) P value (paired t-test or McNemar test)
Echocardiographic parameters      
LVEDd/height, mm/m (n=80) 27.6±2.8 27.7±2.7 0.71
LVESd/height, mm/m (n=79) 18.5±2.2 18.4±1.9 0.74
LV mass index, g/m2 (n=76) 44±10 45±8 0.59
EF, % 59.8±3.9 59.1±3.9 0.12
LA volume index, ml/m2 (n=78) 22.8±5.5 23.7±6.3 0.27
E, cm/s 73±17 77±18 0.095
A, cm/s 72±19 77±20 0.003
E/A 1.2±1.1 1.0±0.3 0.17
Deceleration time, ms 210±35 204±42 0.26
e’ lateral, cm/s 11.4±3.5 11.2±2.9 0.40
E/e’ 6.9±2.2 7.4±2.6 0.029
Systolic PAP (n=36) 30±6 29±6 0.29
TAPSE (n=59) 22±4 21±4 0.80
Right ventricular S’(n=70) 13±2 13±2 0.73
Global longitudinal strain, % (n=76) -20.1±2.5 -20.1±2.4 0.93
Diastolic function     0.44
Normal 46 (56.8%) 47 (58.0%)  
Grade I DD 33 (40.7%) 28 (34.6%)  
Grade ≥2 DD 2 (2.5%) 6 (7.4%)  
Table 3: Comparison of echocardiographic parameters at baseline and follow-up. Abbreviations as per table 2.