Advantages Disadvantages
Culprit lesion only revascularization The culprit lesion is treated and the more unstable plaque is treated
The procedure is shorter
Less contrast agent
Less renal impairment
Staff discussion is possible later
Reevaluation of the lesions (-often overestimated during the emergency procedure, especially because of coronary spasms)
Easier to obtain an informed consent, easier to inform the patient on different options and to take into account his preferences.
opportunity to prove myocardial ischemia by functional test or FFR
Unstable plaques remaining are not treated
Hemodynamic stenoses are not treated
Longer hospitalization (in case of staged procedure)
Requiring 2 arterial punctures
Full revascularization All the significant lesions are stabilized and treated
Shorter hospitalization
Only one arterial puncture
enhance of the collateral blood flow
greater myocardial salvage
achievement of a complete revascularization, factor that is associated with a better prognosis
peri-procedural complications
More severe in case of stent thrombosis
Longer procedure
Hemodynamic instability during balloon inflations
Vessel related complications (dissections, no-reflow)
More contrast agent
More renal impairment
No staff discussion, no heart team
Table 1: Comparison of the two different options in case of multivessel disease revealed by a STEMI