NTP B-L NTP iNO B-L iNO SIL B-L SIL SIL/NO
mPAP, mmHg 42.49 ± 7.27 23.79 ± 8.30a 41.22 ± 7.05 40.53 ± 7.25 43.76 ± 7.49 36 ± 9.43b 35.33 ± 9.34c
mABP, mmHg 92.26 ± 13.81 72.5 ± 10.45a 89.49 ± 13.40 92.16 ± 16.31 95.02 ± 14.23 88.23 ± 14.30 88.22 ± 13.40
PAWP, mmHg 27.24 ± 6.94 13.81 ± 6.52a 26.42 ± 6.73 32.07 ± 7.23d 28.06 ± 7.15 25.24 ± 8.24 26.91 ± 8.70
TPG, mmHg 15.15 ± 4.33 9.99 ± 3.69a 14.69 ± 4.20 8.57 ± 4.66e 15.6 ± 4.46 10.76 ± 3.98c 8.43 ± 3.90cf
CI, l/min/m2 1.96 ± 0.39 2.78 ± 0.71a 1.9 ± 0.38 1.87 ± 0.42 2.02 ± 040 2.24 ± 0.40g 2.12 ± 0.47
PVRI, WU/m2 8.09 ± 3.31 3.59 ± 1.05a 7.84 ± 3.21 4.85 ± 3.39e 8.33 ± 3.40 5.06 ± 2.38c 4.24 ± 2.28c
SVRI, WU/m2 41.6 ± 10.82 24.85 ± 7.80a 40.35 ± 10.50 44.94 ± 13.44 42.85 ± 11.15 36.68 ± 9.91g 38.04 ± 9.65
PVRI/SVRI Ratio 0.195 ± 0.057 0.154 ± 0.06h 0.195 ± 0.056 0.104 ± 0.055e 0.195 ± 0.056 0.136 ± 0.048c 0.107 ± 0.047c
Data presented are mean ± standard deviation. Statistical analysis was performed using Mann-Whitney U test. a is for P<0,001 between NTP and NTP B-L, b is for P<0,01 between SIL and SIL B-L, c is for P<0,001 between SIL and SIL B-L, d is for P<0,05 between iNO and iNO B-L, e is for P<0,001 between iNO and iNO B-L, f is for P<0,05 between SIL/NO and SIL, g is for P<0,05 between SIL and SIL B-L, h is for P<0,05 between NTP and NTP B-L. B-L:Baseline (equilibrium) measurements
Table 3: Hemodynamic measurements obtained during right heart catheterization and vasoreactivity testing with studied drugs.