plasma
Figures 3A, B, C, D: Estimation of plasma peak concentration (Cmax, ng/ml) of δ-, γ-, δ, α-tocotrienol of various doses: The single dose of 125 mg, 250 mg, or 500 mg of DeltaGold-based δ-tocotrienol was administered in one day to well-fed healthy subject (11/dose). The blood samples were collected in ethylene diamine tetra acetic acid (EDTA) glazed tubes at pre-dose (0 h) to post-dose 1 h, 2 h, 3 h, 4 h, 6 h, 8 h, 10 h intervals of each subject. The plasma samples were harvested and processed to carry out normal phase HPLC analyses of each subject as described in Material and Method section. Values are means ± standard deviation (n = 11/dose). Values are significantly different at P<0.001 from each other.