δ-Tocotrienol        
# Cytokines 0-hr 3-hr 0-hr 3-hr 0-hr 6-hr    
    125mg/day 250mg/day 500mg/day Description Functions
I Cytokinesinvolvedininflammation.          
1 GM-CSF 100 89 100 71 100 44 Granulocyte Macrophage Colony Stimulating Factor It plays a key role in inflammatory and autoimmune disease
2 IL-13 100 76 100 66 100 42 Interleukin-13 Key role in the activities of natural killer cells and T lymphocytes.
3 Eotaxin-3 100 87 100 67 100 71 Chemokine ligand 26 It activates eosinophils, basophils and Th2 type T lymphocytes, stimulated with interleukin 4.
4 PIGF-1 100 67 100 58 100 55 Plasmenogen Activator Inhibitor-1 A multitask cytokine involed in various types of inflammation.
5 G-CSF 100 88 100 81 100 40 Granulocyte Colony Stimulating Factor Stimulates proliferation, differention, function of neutrophil precursor.
6 Rantes 100 76 100 71 100 39 Regulated upon activation normal T-cell expressed It induces proliferation/activation of certain natural-killer cells,also an HIV-suppressive factor.
II Cytokinesinvolvedincardiovasculardiseases.      
7 β-NGF 100 78 100 73 100 56 β-Nerve Growth Factor Exerts a variety of effects in the cardiovascular system and on endothelial cells.
8 Adipo 100 189 100 261 100 289 Adiponectin (GBP-28) Adipocyte-secreted insulin-sentizing and antiatherosclrrotic hormone. Its low level resulted decline in insulin sensitivity in humans.
III Cytokinesinvolvedincancer.          
9 SCF 100 84 100 86 100 82 Stem Cell Factor Tumor-induced brain injury/brain cell-mediated SCF expression leads to tumor growth.
10 TGF-β1 100 146 100 167 100 734 Tumor growth Factor-β1 Cytokine controls proliferation, adhesion, migration & other functions in many cells.
IV Cytokinesinvolvedinageing.          
11 Leptin 100 193 100 289 100 341 Leptin Regulating energy intake/energy expenditure by drcreasing appetite/increased metabolism
Table 6: Cytokines of plasma samples of pharmacokinetic of δ-tocotreinol-125 mg-0 h versus 3 h; 250 mg-0 h versus 3 h; or 500 mg-0 h versus 6 h in one day in humans.