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Figure 4: Total plasma concentrations (ng/ml) of four isomers of tocotrienols and tocopherols of various doses: The doses of 750 mg or 1000 mg/d of DeltaGold-based δ- tocotrienol were administered to healthy fed subjects. The plasma samples were collected at different time points and processed to carry out normal phase HPLC analyses as described in Material and Method section. The total plasma concentrations of each isomer of tocotrienols and tocopherols were compared for each dose. Values are means ± standard deviation (n=3/dose). Values are significantly different compared to 750 mg dose versus 1000 mg dose at *P<0.05; or **P<0.01 from each other. |