| Subjects:1 - 3. |
Normal Phase-Silica column. |
| Tocols-------> |
δ-Tocotrienol |
γ -Tocotrienol |
β-Tocotrienol |
α -Tocotrienol |
δ-Tocopherol |
γ -Tocopherol |
β -Tocopherol |
α -Tocotrienol |
| Hour |
ng/ml |
ng/ml |
ng/ml |
ng/ml |
ng/ml |
ng/ml |
ng/ml |
ng/ml |
| 0 Hr. |
132 ± 12* |
795 ± 19* |
1145 ± 61* |
241 ± 16* |
894 ± 69* |
319 ± 30* |
542 ± 11* |
1644 ± 59* |
| 1 hr. |
310 ± 28 |
1035 ± 10 |
1565 ± 62 |
268 ± 13 |
949 ± 11 |
404 ± 44 |
525 ± 54 |
2080 ± 68 |
| 2 hr. |
877 ± 24 |
1183 ± 16 |
1568 ± 77 |
278 ± 7 |
1195 ± 69 |
433 ± 26 |
599 ± 14 |
2002 ± 91 |
| 4 hr. |
1444 ± 53 |
1352 ± 23 |
1885 ± 91 |
293 ± 11 |
1348 ± 93 |
547 ± 12 |
704 ± 29 |
2231 ± 35 |
| 6 hr. |
759 ± 30 |
361 ± 74 |
1538 ± 22 |
223 ± 5 |
726 ± 51 |
273 ± 67 |
621 ± 28 |
2754 ± 84 |
| 8 hr. |
523 ± 13 |
329 ± 17 |
137 ± 102 |
86 ± 16 |
432 ± 45 |
212 ± 16 |
278 ± 16 |
2406 ± 51 |
| Total tocols (ng/ml) |
4045 |
5055 |
7838 |
1389 |
5544 |
2188 |
3269 |
13117 |
|
| *Values represent ± Standard Deviation (± SD). |
| Table 2: Estimation of plasma tocols by normal phase HPLC of pharmacokinetic human study after feeding single dose of 750 mg of δ -tocotrienol in one day. |
