Subjects: 4 - 6. Normal Phase-Silica column (NP). Tocols-------> δ -Tocotrienol γ -Tocotrienol β -Tocotrienol α -Tocotrienol δ -Tocopherol γ -Tocopherol β -Tocopherol α -Tocopherol Hour ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml ng/ml 0 Hr. 173 ± 11* 843 ± 13* 1220 ± 93* 292 ± 39* 888 ± 22* 330 ± 34* 639 ± 38* 1817 ± 80* 1 hr. 360 ± 20 1065 ± 7 1516 ± 21 653 ± 42 986 ± 18 412 ± 17 763 ± 69 2025 ± 66 2 hr. 993 ± 33 1251 ± 32 1830 ± 91 807 ± 49 1266 ± 25 457 ± 33 1025 ± 58 2115 ± 92 4 hr. 1593 ± 44 1387 ± 10 1937 ± 72 1125 ± 35 1473 ± 71 589 ± 39 1525 ± 32 2228 ± 22 6 hr. 884 ± 45 484 ± 17 1315 ± 48 375 ± 49 765 ± 44 241 ± 28 717 ± 56 2915 ± 35 8 hr. 562 ± 47 374 ± 27 519 ± 20 309 ± 17 500 ± 25 183 ± 14 516 ± 51 2139 ± 61 Total tocols (ng/ml) 4565 5404 8337 3561 5878 2212 5185 13239

*Values represent ± Standard Deviation (± SD).

Table 3: Estimation of tocols by normal phase HPLC of pharmacokinetic human study after feeding single dose of 1000 mg of δ -tocotrienol in one day.