|  | 1st cross-sectional evaluation | 2nd cross-sectional evaluation | P | 
          
            | Maximum HR [Z-score] | median-1.43
              (-2.32 - -0.58) | median-1.54
              (-3.07 - -0.17) | NS | 
          
            | VO2 max [Z-score] | mean-2.05 (1.09) | mean-1.74 (0.88) | 0.034 | 
          
            | VO2 max Z-score < -2Z | 37/68 (54.4%) | 33/67 (49.3%) | NS | 
          
            | Pulse oxygen at 1.5W/kg [Z-score] | NA | median-0.84*
              (-1.79 – 0.11) | - | 
          
            | Pulse oxygen at maximum exercise[Z-score] | median-1.27
              (-2.15 – -0.51) | median-1.31*
              (-2.19 – -0.63) | NS | 
          
            | Arterial systolic hypertension at rest | NA | 9/87 (10.3%) | - | 
          
            | Arterial systolic hypertension at 1.5W/kg | NA | 9/79 (11.4%) | - |