|
|
|
CAD Patients* |
|
Patients with Mild or No CAD† |
|
|
|
|
|
|
rs1333049 genotype |
|
rs1333049 genotype |
|
|
|
Characteristic |
GG |
GC |
CC |
|
GG |
GC |
CC |
|
Age (years) |
|
55 ± 9 |
55 ± 8 |
55 ± 8 |
|
68 ± 10 |
69 ± 9 |
69 ± 10 |
Sex (male) |
|
78% |
78% |
80% |
|
57% |
50% |
53% |
Diabetes |
|
0% |
0% |
0% |
|
0% |
0% |
0% |
BMI (kg/m2) |
|
30 ± 6 |
29 ± 5 |
29 ± 6 |
|
28 ± 7 |
28 ± 6 |
28 ± 6 |
Hypertension |
|
54% |
56% |
50% |
|
43% |
39% |
37% |
Hyperlipidemia |
61% |
62% |
63% |
|
27% |
24% |
27% |
|
Smoking |
|
25% |
29% |
25% |
|
11% |
10% |
9% |
Family CHD History |
43% |
50% |
50% |
|
21% |
18% |
19% |
|
*CAD was defined as clinically-significant 1- (n=937), 2- (n=471), or 3-vessel (n=349) disease of ≥70% stenosis; †Mild CAD was defined as maximum stenosis of 10-<70%, while no disease was defined as no lesion or luminal irregularities (n=1,606, including 152 mild CAD and 1,454 no-CAD) |