Variables

 

All Patients
(n=75)

Lowest Uric Acid
Quartile Patients*
(n=16)

Highest Uric Acid
Quartile Patients*
(n=18)

 

p Value

Age (years)

53.68 ± 7.72

53.12 ± 7.71

52.72 ± 6.95

0.873

Body mass index (kg/m2)

22.99 ± 2.76

22.38 ± 2.45

22.95 ± 1.73

0.442

Male, n (%)

63 (84)

15 (20)

15(20)

0.347

Prior myocardial infarction
n (%)

 

4 (5)

 

2 (2)

 

0 (0)

 

0.122

Risk factor, n (%)
Family history

 

18 (24)

 

6 (8)

 

3 (4)

 

0.169

        Smoker

39 (52)

 8 (10)

8 (10)

0.746

        Hypertension

40 (53)

 9 (12)

9 (12)

0.715

        Diabetes mellitus

16 (21)

          6 (8)

4 (5)

0.329

        Dyslipidemia

52 (69)

13 (17)

12 (16)

0.336

Door to needle (minute)

57.88 ± 43.56

59.43 ± 41.43

51.88 ± 46.08

0.276

Time to reperfusion (minute)
Anterior MCI, n (%)

297.28 ± 154.44
47 (63)

288.18 ± 173.43
10 (13)

264.38 ± 139.70
14 (18)

0.661
0.329

 Lipid Profile      
Total cholesterol (mg/dl)

 

209.70 ± 44.00

 

214.18 ± 54.25

 

217.16 ± 41.77

 

0.857

        LDL cholesterol (mg/dl)

136.80 ± 40.08

144.25 ± 49.54

148.77 ± 33.35

0.754

        HDL cholesterol (mg/dl)

42.93 ± 10.70

43.25 ± 12.05

43.55 ± 11.25

0.939

        Triglyceride (mg/dl)

152.57 ± 69.95

134.06 ± 51.60

135.50 ± 41.58

0.769

Creatinine (mg/dl)

1.03 ± 0.28

1.06 ± 0.26

1.22 ± 0.32

0.109

Medication at enrollment,
n (%)
Diuretic
ACE Inhibitor
Statin
Beta blocker

 

21 (28)
52 (69)
41(54)
23 (30)

 

3 (4)
10 (13)
9 (12)
6 (8)

 

10 (13)
15 (20)
8 (10)
7 (9)

 

0.027
0.169
0.492
0.934

MACE, n (%)

43 (57)

6 (8)

15 (20)

0.006

*Uric acid quartiles: first quartile range <4.8mg/dl, second quartile range 4.8 to 6.2 mg/dl, third quartile range >6.2 to 7.3 mg/dl, fourth quartile range >7.3 mg/dl.
Data are expressed as percentages of patients or mean  ±  SD.
The p value is given for the comparison of lowest versus highest uric acid quartile, for normally distributed, continous variables by t test, for skewed continous variables by Mann-Whitney U test, and for categorical variables by Pearson’s chi-square test.
MACE=Major Adverse Cardiac Event, MCI=myocardial infarction, ACE=angiotensin converting enzyme

Table 1: Baseline Characteristics between the lowest and highest uric acid levels in patients with acute STEMI.