|
| |
Characteristics |
Free-Living Healthy senior subjects |
Hypercholesterolemic subjects |
| |
|
NS-7 capsule |
NS-6 capsule |
NS-7 capsule |
NS-6 capsule |
| |
|
Baseline |
Baseline |
Baseline |
Baseline |
|
|
| 1 |
Subjects |
| |
Males (n) |
20 |
24 |
32 |
20 |
| |
Females (n) |
10 |
15 |
9 |
10 |
|
|
|
|
|
|
|
Total (males + females) n = |
30 |
39 |
41 |
30 |
|
|
|
|
|
|
| 2 |
Age (years) |
| |
Males |
66.20 ± 1.58* |
64.46 ± 1.13* |
61.84 ± 1.60* |
62.25 ± 1.76* |
| |
Females |
59.40 ± 2.48 |
59.60 ± 1.30 |
61.22 ± 2.62 |
53.80 ± 1.87 |
|
|
|
|
|
|
| |
Total (males + females) |
63.93 ± 7.89 |
62.59 ± 0.93 |
61.71 ± 1.35 |
59.43 ± 1.50 |
|
|
|
|
|
|
| 3 |
Body weight (kg) |
| |
Males |
78.85 ± 1.33 |
81.54 ± 0.60 |
77.41 ± 0.79 |
75.90 ± 1.30 |
| |
Females |
72.90 ± 3.44 |
62.27 ± 1.25 |
73.56 ± 2.10 |
65.60 ± 0.75 |
|
|
|
|
|
|
| |
Total (males + females) |
76.73 ± 1.52 |
74.13 ± 1.63 |
76.56 ± 0.80 |
72.47 ± 1.27 |
|
|
|
|
|
|
| 4 |
Body mass index (kg/m2) |
| |
Males |
25.44 ± 0.25 |
25.87 ± 0.16 |
25.12 ± 0.29 |
24.85 ± 0.38 |
| |
Females |
25.86 ± 0.53 |
24.66 ± 0.45 |
25.81 ± 0.33 |
26.85 ± 0.34 |
|
|
|
|
|
|
| |
Total (males + females) |
25.58 ± 0.24 |
25.40 ± 0.22 |
25.27 ± 0.24 |
25.18 ± 0.29 |
|
|
|
|
|
|
| 5 |
Initial cholesterol (mmol/L) |
| |
Males |
4.13 ± 0.17 |
4.42 ± 0.13 |
6.08 ± 0.08 |
6.01 ± 0.08 |
| |
Females |
4.67 ± 0.19 |
4.39 ± 0.14 |
5.97 ± 0.16 |
6.10 ± 0.16 |
|
|
|
|
|
|
|
Total (males + females) |
4.31 ± 0.14 |
4.41± 0.10 |
6.06 ± 0.07 |
6.04 ± 0.08 |
| 6 |
Intial triglycerides (mmo/L) |
|
|
|
| |
Males |
1.37 ± 0.12 |
1.48 ± 0.04 |
2.63 ± 0.31 |
2.48 ± 0.20 |
| |
Females |
1.76 ± 0.20 |
1.59 ± 0.21 |
2.34 ± 0.68 |
2.17 ± 0.35 |
|
|
|
|
|
|
| |
Total (males + females) |
1.50 ± 0.11 |
1.52 ± 0.10 |
2.56 ± 0.28 |
3.37 ± 0.18 |
