Gene Name |
Symbol |
Alias |
% neonatal PDA |
% neonatal mortality |
Reference |
Prostaglandin-endoperoxide synthase 1 |
Ptgs1 |
Cyclooxygenase-1 |
0 |
|
[12] |
Prostaglandin-endoperoxide synthase 2 |
Ptgs2 |
Cyclooxygenase-2 |
33 |
35 |
[12] |
Prostaglandin-endoperoxide synthase 2 |
Ptgs2 |
Cyclooxygenase-2 |
57 |
57 |
[13] |
Prostaglandin-endoperoxide synthase 2a |
Ptgs2 |
|
0 |
0 |
[13] |
Ptgs2 (-/-) and Ptgs1 (+/-) |
|
|
74 |
79 |
[12] |
Ptgs2 (-/-) and Ptgs1 (-/-) |
|
|
100 |
100 |
[12,14] |
Prostaglandin E synthase |
Ptges |
Microsomal prostaglandin E
synthase-1 |
0 |
|
[62] |
Prostaglandin E receptor 4 |
Ptger4 |
PGE receptor EP4 |
>95 |
>95 |
[16-18] |
Solute carrier organic anion transporter family, member
2A1 |
Slco2a1 |
Prostaglandin transporter |
|
100 |
[20] |
Hydroxyprostaglandin dehydrogenase 15-(NAD) |
Hpgd |
Prostaglandin dehydrogenase |
>95 |
>95 |
[21, 22] |